FemtoFiber ultra 1050
Femtosecond fiber laser
Simplifying multi-photon microscopy with stress-less femtosecond lasers
FemtoFiber ultra 1050
Femtosecond fiber laser
In two-photon microscopy, peak-power is brightness! If you care for the best image brightness, you need short pulses, high power, and most importantly a clean temporal pulse shape. The FemtoFiber ultra 1050 features the highest peak power available on the market and hence enables unmatched image brightness.
Additionally, software-controlled dispersion precompensation (GDD) and an integrated AOM for power modulation, make the system extremely user-friendly.
TOPTICA's robust & reliable fiber laser technology significantly reduces the cost of ownership of your laser systems.
The FemtoFiber ultra 1050 is ideally suited for the two-photon excitation of common fluorophores like mCherry, Propidium Iodide, tdTomato, eYFP, DsRed, mRFP or mOrange.
Your Benefits
Compact & Low cost of ownership
Saving table space with all-integrated robust fiber laser system.
Clean Pulse Technology
TOPTICA’s unique Clean Pulse Technology provides clean, pedestal-free pulses even after the fiber for best image brightness.
Images by Shau Poh Chong and Peter Török
User-friendly GDD
Short pulses and software-controlled dispersion precompensation (GDD) for user-friendly handling TOPTICA’s FemtoFiber ultra provides motorized group delay dispersion (GDD) pre-compensation that can be controlled in software. Due to chromatic dispersion, a femtosecond pulse stretches in time when transmitted through optical material in the microscope. GDD pre-compensation adds the opposite dispersion to circumvent this effect by cancelling it out. TOPTICA’s software-controllable GDD pre-compensation ensures short pulses at the sample plane with user-friendly, repeatable optimization of fluorescence signal strength via the graphical user-interface (GUI).
Fast power control
An integrated acousto-optic modulator (AOM) enables fast power-modulation and flyback blanking in synchronization with the beam scanner. This minimizes sample damage and photo-bleaching. Also, a fast electronic trigger output is available as reference for TCSPC in FLIM and gated detection.
For all important fluorophores
The FemtoFiber ultra 1050 is ideally suited for the two-photon excitation of common fluorophores like RFP, mCherry, Propidium Iodide, tdTomato, eYFP, DsRed, mOrange, auto-fluorescence or SHG-imaging.
More than 20 years of experience
TOPTICA is drawing upon 20 years of experience in developing OEM-class fiber lasers. We have tailored our FemtoFiber ultra series to provide our customers with an industrial-grade light engine for high-end applications. The reliable and compact laser design provides femtosecond pulses with high average power, excellent temporal and spatial beam quality.
Specifications
Literature
Papers
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A cortical basis for perception of internal gut sensations
Omer Rafael, Stav Shtiglitz, Juliet Miller, Yael Prilutski, Itay Talpir, Ayal Lavi, Yoav Livneh, bioRxiv 2026.02.11.705298; (February 2026) -
Feedforward and feedback population dynamics during binocular conflict in mouse visual cortex
Melina Timplalexi, William M. Connelly, Adam Ranson, bioRxiv 2025.10.02.679998 (October 2025) -
The functional organisation of retrosplenial feedback to V1
Melina Timplalexi, Pedro Mateos-Aparicio, William M. Connelly, Adam Ranson, bioRxiv 2025.09.25.678583 (September 2025) -
From perception to valence: a pair of interneurons that assign positive valence to sweet sensation in Drosophila
Kevin William Christie, Tarandeep Singh Dadyala, Phuong Chung, Masayoshi Ito, Lisha Shao, bioRxiv 2025.10.31.685871 (November 2025) -
Sponges as bioindicators for microparticulate pollutants?
(2021) -
Spectral pulse shaping of a 5 Hz, multi-joule, broadband optical parametric chirped pulse amplification frontend for a 10 PW laser system
František Batysta et al. in Optics Letters (2018)
Articles
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Simplifying two-photon microscopy
Wiley Analytical Science -
Automated femtosecond fiber delivery for multiphoton microscopy
Laura Lohr and Joseph Mastron et al. in Proc. SPIE Paper 13856-12, Multiphoton Microscopy in the Biomedical Sciences XXVI, Conference 13856 (2026) -
Femtosecond fiber delivery at 920 nm for two-photon microscopy
Konrad Birkmeier, et al. in Proc. SPIE 12847, Multiphoton Microscopy in the Biomedical Sciences XXIV, 1284703 (March 2024) -
Faserlaser für die Spektroskopie
M. Breuer et al. in Best of Physik Journal (2017)
Application Notes
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Next generation two-photon microscopy using the FemtoFiber ultra 920 fiber laser
Dr. Max Eisele, Bernhard Wolfring (2019) -
Time-resolved microscopy and spectroscopy using asynchronously synchronized fiber lasers
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Setting Up a Simple and Cost-Efficient Two-Photon Microscope for Neuroscience
Max Eisele -
Automated Femtosecond Fiber Delivery for Multiphoton Microscopy, Webinar
Luisa Hofmann, BioPhotonics (2025)